A 75-year-old woman presented with a bluish discoloration, measuring 1
cm in diameter, on the dorsal surface of the terminal phalanx of her
right index finger. The patient reported that she had stuck the tip of
her finger with a lead pencil 50 years earlier. At the time, the point
of the pencil had broken off and remained lodged in her finger. In the
intervening years, the mass had slowly enlarged, changed color, and
become tender (Panel A, arrow). Histologic examination of a biopsy
specimen (Panel B) showed degenerative tissue with calcification
(arrows) and granulomas associated with histiocytes laden with fragments
of black graphite. On the basis of the clinical presentation and
pathologic findings, we determined this lesion to be a pencil-core
granuloma. The core of a pencil is composed of graphite, clay, wax, and
lacquer. Each of these components may cause delayed granulomatous
reactions in the skin. Thus, as in this case, pencil-tip injury should
be considered when black granular fragments are found in cutaneous
tissue. The pencil granuloma was not removed, in accordance with the
patient's wishes. After 10 months of clinical observation, there were no
changes in its size or color.
sumber: http://www.nejm.org
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